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Cat. No. | Product Name | Target | Signaling Pathways |
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T19304 |
EC-17 disodium salt
|
Others | Others |
The peak excitation and emission wavelengths of EC-17 are 470/520 nm.EC-17 (disodium salt) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. | |||
T77908 |
Farletuzumab ecteribulin
MORAb-202 |
||
Farletuzumabecteribulin(MORAb-202)是一款人源化抗人叶酸受体α(FRA)抗体Farletuzumab与Mal-PEG2-Val-Cit-PAB-eribulin通过还原的链间二硫键偶联成的抗体-活性分子偶联物(ADC)。该化合物活性分子抗体比率为4.0,对FRA阳性细胞展示出强大的体外细胞毒性,并具备有效的抗肿瘤活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00147 |
FOLR1 Protein, Human, Recombinant (hFc)
Folate receptor 1,Folate rece... |
Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPJ-00148 |
FOLR1 Protein, Rhesus macaque, Recombinant (His)
FR-alpha,Adult folate-binding protein,Ovar... |
Rhesus | HEK293 Cells |
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60. | |||
TMPK-00150 |
FOLR1 Protein, Human, Recombinant (His & Avi)
Folate receptor 1,Folbp1,Folate <... |
Human | HEK293 Cells |
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t... |